
Boundless Bio Unveils ecDNA-Directed Cancer Therapy Strategy in New Presentation

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Boundless Bio Inc. has unveiled a new cancer therapy strategy targeting oncogene amplified cancers, focusing on extrachromosomal DNA (ecDNA). Their drug discovery platform, Spyglass, identifies synthetic lethal targets, with BBI-940, an oral Kinesin degrader, set for clinical trials in 2026. The pipeline includes four other ecDNA-selective targets, and the company has a cash runway extending into the second half of 2028 to support ongoing R&D. The full presentation is available via the provided link.
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